Project Description
Burn injuries are very common and frequently occur in developing countries including Pakistan. In these areas peoples are bound to use traditional ointments. Scientific studies and researches have shown that there are some plants which can heal the wound injuries more effectively than other medicines. The quality of leads arising from natural products is better and is often more biologically friendly due to co-evolution with receptor sites of biological system. Equisetum arvense belonging to the family Equisetaceae is an herbaceous perennial plant, also known as the field horsetail and is distributed in the Naran Valley. Monotheca buxifolia is a monotypic genus of the family Sapotaceae, locally known as “Gurgura”. It is an evergreen fruit-producing medicinal tree, distributed in North-west Pakistan. In the present study the plants which will be screen out are Equisetum arvense and Monotheca buxifolia.These plants will be collected, shade dried and the plant will be extracted using different organic solvents. Each extract will be tested and bioactive part will be subjected to fractionation and chromatographic analysis and isolation. Beside these plant extracts and its subsequent fractions will be evaluated for potential pharmacological activities, antibacterial and antifungal activity with special reference to the burn wound healing.
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