Research At COMSATS

Synthetic Organic Chemistry

Dr. Muhammad Arfan

	Designation:	Assistant Professor (HEC Approved Supervisor)
	Email:	marfan@cuiatd.edu.pk
	Phone No. :	0092-(0)992-383591-6 Extension #372\|
	Role:	Faculty
	Research Interests:	(i) β-peptides Synthesis (ii) Synthesis of peptide drugs (iii) Reagents in organic synthesis (iv) Develop new methodologies

Projects

Structure Identification Of Microbial Metabolites Department Of Organic And Bimolecular Chemistry,

Publications/Papers

2013

Journal

M.Arfan "Biological Evaluation of Chiral Amides Synthesized from Diacetyl-L-tartaric Acid and Aromatic Amines," , ASIAN JOURNAL OF CHEMISTRY ,Volume 25 ,Issue 2 ,Page 745-748 , 2013

2012

Journal

M.Arfan "Asymmetric Induction via Metalation of Succinic Esters and Amide using S(+) Menthol and R(+) 1-Phenylethylamine as Chiral Auxiliaries" , Letters in Organic Chemistry ,Volume 9 ,Issue 9 ,Page 632-638 , 2012

M.Arfan "Furanone Derivatives from Terrestrial Streptomyces spp. " , Natural Product Communications ,Volume 7 ,Issue 9 ,Page 1199 - 1202 , 2012

2010

Journal

M.Arfan "A New Method of Reducing 2-Mercapto-Substituted 1,3,4-Oxadizoles: Synthesis of Acylhydrazine Derivatives" , Letters in Org. Chem. ,Volume 7 ,Page 411-414 , 2010

2009

Journal

Rashid Iqbal,Khalid M. Khan,Javaid H. Zaidi,Zia Ullah,Muhammad Zareef,M.Arfan "A convenient synthesis of p-substituted 1-arylsulfonyl-pyrrolidin-2-ones" , Natural Product Research ,Volume 23 ,Issue 5 ,Page 485–488 , 2009

2008

Journal

M.Arfan "2-[4-Benzyl-5-(2-furyl)4-H-1,2,4- triazole -3-ylsufanyl]acetamide " , Acta Cryst. Section E. ,Volume 64 ,Page O1259. , 2008

M.Arfan "N`-( 2-flurobenzoyl) benzohydrazide " , Acta Cryst. Section E. ,Volume 64 ,Page o1128 , 2008

M.Arfan "4-Ethyl -3-(3-pyridyl)-1H-1, 2, 4-triazole-5(4H)-thione 0.095-hydrate " , Acta Cryst. Section E. ,Volume 64 ,Page o945 , 2008

M.Arfan "Ethyl 2-(5-phenyl-1,3,4-oxadiazole-2-ylsulfanyl) acetate " , Acta Cryst. Section E. ,Volume 64 ,Page o736 , 2008

M.Arfan "A Novel Synthesis and Antimicrobial Activity of 1-[(Substitutedphenyl sulfonyl] pyrrolidin-2-ones. " , J. Enzyme Inhibition Med. Chem. ,Volume 23 ,Issue 1 ,Page 82-86 , 2008

M.Arfan "In Situ Synthesis of Benzyl Chloromethyl Ether and its Use for the Protection and Deprotection of Bifunctional Hydroxyl Compounds" , Letters in Org. Chem. ,Volume 5 ,Page 125.127 , 2008

M.Arfan "N-protected L-Amino acids As Their Benzoxymethyl (BOM) Esters. " , Letters in Org. Chem ,Volume 22 ,Issue 1 ,Page 22-25 , 2008

2007

Journal

M.Arfan "Synthesis, Anti-malarial and Anti-HIV Activities of Novel Chiral and Achiral benzenesulfonamides bearing 1, 3, 4-oxadizole moieties;" , J. Enzyme Inhibition Med. Chem ,Volume 22 ,Issue 3 ,Page 301-308 , 2007

M.Arfan "A Convenient Synthesis of 6, 8-Dimethoxy-3-[(2-(4- methoxy phenyl)ethyl] isocoumarin" , Chinese Journal of Chemistry ,Volume 25 ,Page 102-104 , 2007

M.Arfan "Synthesis,Anti- HIV and Anti- fungal Activities of Novel Benzenesulfonamides Bearing 2, 5-disubstituted-1,3,4 Oxadiazole Moiety. " , J. Phosphorus, Sulfur, Silicon & Related Elements ,Volume 18 ,Issue 2 ,Page 281 - 298 , 2007

Muhammad Zareef,Rashid Iqbal,Najam A. Al-Masoudi,Javaid H. Zaidi,M.Arfan "Microwave Assisted Synthesis and Anti-HIV Activity of Novel benzenesulfonamides Bearing 2,5-disubstituted -1,3,4-oxadiazole moiety" , Heteroatom Chemistry ,Volume 18 ,Issue 4 ,Page 425-431 , 2007

M.Arfan "Microwave Assisted Synthesis and Anti-HIV Activity of Novel benzenesulfonamides Bearing 2,5-disubstituted -1,3,4-oxadiazole moiety. " , Heteroatom Chemistry ,Volume 18 ,Issue 4 ,Page 425-431 , 2007

M.Arfan "N00 0 -(4-Fluorobenzoyl)-3,4,5-trimethoxy- benzohydrazide monohydrate" , Acta Cryst. Section E. ,Volume 63 ,Page o3052 , 2007

M.Arfan "Ethyl 2-(benzoyloxy)benzoate" , Acta Cryst. Section E. ,Volume 63 ,Page o744–o745 , 2007

2006

Journal

M.Arfan "Crystal structure of 2-bromobenzoic acid hydrazide, C7H7BrN2O" , Z. Kristallogr. NCS ,Page 305-306 , 2006

M.Arfan "Carbonic anhydrase inhibitors. Inhibition of human tumor-associated isozymes IX and cytosolic isozymes I and II with some 1,3,4-oxadiazole-thiols" , J. Enzyme Inhibition Medicinal. Chemistry ,Volume 21 ,Issue 4 ,Page 351–359 , 2006

M.Arfan "3,4,5- Trimethoxy Benzohydrazide hemihydrate." , Acta. Cryst. Section E. ,Volume 62 , 2006

M.Arfan "A Convenient Synthesis and Antibacterial Activities of Symmetrical and Asymmetrical 2, 5-Disubsituted 1, 3, 4-Oxadiazoles. " , Jour.Chem Soc. Pak. ,Volume 28 ,Issue 2 ,Page 165-168 , 2006

M.Arfan "1- [(4- Methylphenyl)sulfonyl]pyrrolidin-2-one." , 2006 ,Volume 62 ,Page 02955-02957 , 2006

M.Arfan "Reactions of N-Protected Amino Acids with Alkyl chloromethyl ethers and Chloromethyl Sulfide. " , Letters in Org. Chem ,Volume 3 ,Page 242-243 , 2006

M.Arfan "4-Methyl-N-[1-(5-(thioxo-4,5-dihydro-1,3,4-oxadizol-2-yl)propyl]Benzene sulfonamide" , Acta Crystallographic Section E ,Volume 62 ,Page o2481-o2483. , 2006

M.Arfan "N- Benzoyl-N`-methyl-N` (p-tolylsulfony) hydrazine." , Acta Crystallographica Section E ,Volume 62 ,Page o3049-o3051 , 2006

2005

Journal

M.Arfan "Synthesis of Some New Dihalophenyl- and Dihalobenzylisocoumarins and Their (dl)-3,4-Dihydroderivatives" , Turk. J. Chem. ,Volume 29 ,Page 321-325 , 2005

2003

Journal

M.Arfan "Chemical Constituents of Taxus wallichiana Zucc." , Jour.Chem. Soc. Pak. ,Volume 25 ,Issue 4 ,Page 337-340 , 2003