Project Description
With the increase in antibacterial drug development resistance of bacteria against the antibacterial drugs is increasing day by day. This problem has triggered the attention of the scientists to introduce new antibacterial drugs. Carboxylic acid substituted Quinolone derivatives are famous for their broad spectrum activities as antimicrobial agents. They are active against the both gram negative bacteria as well as gram positive strains of bacteria. The current project is about the synthesis of some quinolone carboxylic acid substituted oxadiazole, triazoles and triazole amine starting from their common precursor hydrazides. Structures of all the synthesized compounds will be confirmed by IR, 1HNMR,13CNMR spectral analysis. As literature reveals the antibacterial significance of the quinolone carboxylic acids, all the synthesized compounds will subjected to their antibacterial assays against the gram positive and gram negative strains of bacteria.
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