Research At COMSATS

Pharmaceutics Research Group

Dr. Muhammad Imran Amirzada

	Designation:	Associate Professor
	Email:	imranamirzada@cuiatd.edu.pk
	Phone No. :	N/A
	Role:	Faculty
	Research Interests:	- Recombinant Protein expression and purification - Cancer cells / MDR Cells proliferation - Recombinant protein nanoparticles

Academics/ Degrees

Ph.D 2014 Jiangnan University, Wuxi. China

MS 2005 Liverpool John Moores University, Liverpool. UK

B. Pharmacy 2002 University of Balochistan, Quetta. Pakistan

Profile/Bio

September. 2014 - January. 2016. Assistant Professor, Faculty of Pharmacy. University of Sargodha, Sargodha. Pakistan
July. 2009 – July. 2010. Quality Control / Assurance Officer, Aims Pharmaceuticals Islamabad Pakistan
December. 2007 – June. 2009. Research Officer, Biopharmaceutical Laboratory, Center of Excellence in Molecular Biology (CEMB), University of The Punjab, Lahore, Pakistan
October. 2002 – September.2003.Pharmacist, Wilson’s Pharmaceuticals Islamabad. Pakistan.

Projects

PEGYLATED PROTAMINE – RECOMBINANT HUMAN INTERLEUKIN 24 AND DOXORUBICIN NANOPARTICLES FOR SINGLE COMBINATION THERAPY OF CANCER

Publications/Papers

2023

Journal

I.Amirzada,J.Sharif,Khan Q "Potential drug-drug interactions in patients presenting with osteoarthritis to community orthopaedic clinics of Abbottabad, Khyber Pakhtunkhwa: a cross-sectional study" , Annales Pharmaceutiques Françaises , 2023

I.Amirzada "Computational Modeling, High-Level Soluble Expression and In Vitro Cytotoxicity Assessment of Recombinant Pseudomonas aeruginosa Azurin: A Promising Anti-Cancer Therapeutic Candidate" , Pharmaceutics ,Volume 15 ,Page 1825 , 2023

I.Amirzada "Evaluation of Exosomes Encapsulated Recombinant Interleukin-29 for its in vitro Anticancer Studies" , Journal of Biotechnology ,Volume 373 ,Page 24-33 , 2023

2022

Journal

I.Amirzada "Photodynamic cytotoxic and antibacterial evaluation of Tecoma stans and Narcissus tazetta mediated silver nanoparticles. " , Arabian Journal of Chemistry ,Volume 15 ,Page 103652 , 2022

I.Amirzada "PEGylated Protamine Letrozole Nanoparticles: A Promising Strategy to Combat MCF-7 Human Breast Cancer Cells" , Biomed Research International , 2022

I.Amirzada "Design and Evaluation of pH Sensitive PEG-Protamine Nanocomplex of Doxorubicin for Treatment of Breast Cancer" , Polymers , 2022

Dr. Nighat Fatima,I.Shahzadi,A. Mannan,Dr. M. Arfat Yameen,T.Ismail,I.Amirzada,Syed Aun Muhammad,Hina Tariq,G. Murtaza "Photodynamic cytotoxic and antibacterial evaluation of Tecoma stans and Narcissus tazetta mediated silver nanoparticles" , Arabian Journal of Chemistry ,Volume 15 ,Issue 13 ,Page 103652-62 , 2022

Conference

I.Amirzada "Exosomes mediated delivery of Recombinant Human Interleukin 24 for breast cancer" , Journal of Extracellular Vessicle , 2022

2021

Journal

I.Amirzada "Therapeutic potential of Moringa oleifera seed polysaccharide embedded silver nanoparticles in wound healing" , International Journal of Biological Macromolecules ,Page 144-158 , 2021

Asad. M.H.H.B,A. Mannan,I.Amirzada "Fabrication of Carbamazepine Cocrystals: Characterization, In Vitro and Comparative In Vivo Evaluation" , BioMed Research International ,Volume 2021 ,Page 1-9 , 2021

2020

Journal

I.Amirzada "Preparation and nanoencapsulation of Lectin from Lepidium sativum on Chitosan Tripoly Phosphate Nanoparticles and their cytotoxicity against Hepatocellular Carcinoma Cells (HEPG2)" , BioMed Research International ,Volume 2020 , 2020

I.Amirzada "Antiprotease activity of indigenous medical plants against Pakistani Echis carinatus venom" , Pharmacognosy Magazine ,Volume 16 ,Issue 69 ,Page 416-421 , 2020

I.Amirzada "Synthesis, Characterization and docking studies of amide ligands as antileishmanial agents " , Pakistan Journal of Pharmaceutical Sciences ,Volume 33 ,Issue 1 ,Page 385-392 , 2020

I.Amirzada "Effect of varying quantities of polymer on preparation and stability evaluation of carbamazepine cocrystals with dicarboxylic acid coformers " , Pakistan Journal of Pharmaceutical Sciences ,Volume 33 ,Issue 4 ,Page 1755-1761 , 2020

I.Amirzada "Verapamil Hydrochloride nanoparticles formulated with chitosan and sodium alginate by an ionic gelation method" , Tropical Journal of Pharmaceutical Research , 2020

A. Mannan,Asad. M.H.H.B,Dr. M. Arfat Yameen,I.Amirzada,Shujaat A.K, SA Khan "Effect of varying quantities of polymer on preparation and stability evaluation of carbamazepine cocrystals with dicarboxylic acid coformers" , Pakistan Journal of Pharmaceutical Sciences ,Volume 33 ,Issue 4 ,Page 1755-1761 , 2020

2018

Journal

I.Amirzada,M. Sohail "Doxorubicin Nanoparticles prepared by the ionic gelation method with use of Sodium Alginate as polymer" , Tropical Journal of Pharmaceutical Research ,Volume 17 ,Issue 12 ,Page 2329-2334 , 2018

T.Ismail,Dr. Nighat Fatima,A. Mannan,I.Amirzada "Prioritizing and modelling of putative drug target proteins of Candida albicans by systems biology approach" , Acta Biochimica Polonica ,Volume 65 ,Issue 2 ,Page 209–218, , 2018

2016

Journal

A. Mannan,Syed Aun Muhammad,Fareeha Anwar,I.Amirzada,.Nisar-ur-Rahman,Dr. Nighat Fatima,T.Ismail "AN EMERGING PARADIGM EXOSOMES: COMPOSITION, BIOLOGICAL FUNCTIONS, AND DIAGNOSTIC AND THERAPEUTIC POTENTIALS" , INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES, October 2016 ,Volume 3 ,Issue 10 ,Page 1297-1308 , 2016

2014

Journal

I.Amirzada "Cost effective production of recombinant Human Interleukin 24 by lactose induction and a two step denaturing and one-step refolding method" , Journal of Industrial Microbiology & Biotechnology ,Volume 41 ,Issue 1 ,Page 135 - 142 , 2014

I.Amirzada "Recombinant human interleukin 24 reverses Adriamycin resistance in a human breast cancer cell line" , Pharmacological Reports ,Volume 66 ,Issue 0 ,Page 915 - 919 , 2014

I.Amirzada "A conventional method for fermentation and purification of recombinant human interleukin 24 from E.coli" , International Journal of Pharma Research & Review ,Volume 3 ,Issue 1 ,Page 41-44 , 2014

2012

Journal

I.Amirzada "Therapeutic applications of Interleukin 24 (IL24). A Review" , Tropical journal of Pharmaceutical Research ,Volume 6 ,Issue 0 ,Page 1023 - 1027 , 2012

Associations/Memberships

Registered Pharmacist. Punjab Pharacy council, Lahore, Pakistan

Awards/ Appreciations

As Ph.D. student at Jiangnan University, China

Second Presidential scholarship Award for year 2012 – 2013

Second Presidential scholarship Award for year 2011 – 2012

Third Presidential scholarship Award for year 2010 - 2011